Article
Analysis of cerebellum proteomics in the hydrocephalic H-Tx rat.
Neuroreport - 25 Apr 2005
Li Xianfeng, Miyajima Masakazu, Mineki Reiko, Taka Hikari, Murayama Kimie, Arai Hajime
Abstract excerpt
The H-Tx rat is a polygenic inherited model of hydrocephalus. In order to identify disease-specific biomarkers associated with congenital hydrocephalus, comparative proteomic analysis was used to screen cerebellum proteins in H-Tx rats at 1 day after birth. Seven proteins showed significant changes in hydrocephalic H-Tx rats compared with Sprague-Dawley and normal H-Tx rats, including HMG-1, CDCrel-1A,...
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