Article
Genome-wide linkage analysis of inherited hydrocephalus in the H-Tx rat.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2001
Jones H C, Depelteau J S, Carter B J, Lopman B A, Morel L
Abstract excerpt
Inherited hydrocephalus in humans has received very little attention, most probably because known occurrences are sporadic and systematic investigation is difficult. The H-Tx rat, one of a number of rodent strains with inherited hydrocephalus, has a complex inheritance with more than one postulated susceptibility gene and 40% penetrance. The aim of this study was to perform a genome-wide scan on backcross progeny...
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