Article
Genetic analysis of inherited hydrocephalus in a rat model.
Experimental neurology - 1 Nov 2004
Jones Hazel C, Yehia Baligh, Chen Gin-Fu, Carter Barbara J
Abstract excerpt
Congenital hydrocephalus is a serious neurological disorder with a diverse etiology. Although there is strong evidence for genetic causes, few genes have been identified in humans. The rodent model, the H-Tx rat, has hydrocephalus with an onset in late gestation and a complex mode of inheritance. Ventricular dilatation is associated with abnormalities in the cerebral aqueduct and subcommissural organ....
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