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[Effects of apolipoprotein E genetic polymorphism on susceptibility of depression and efficacy of antidepressants].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Dec 2012

Zhang Jun, Shen Xin-hua, Qian Min-cai, Sun Ju-shui, Zhong Hua, Yang Jian-hong, Lin Min, Li Liang

Abstract excerpt

OBJECTIVE: To assess the effects of apolipoprotein E (APOE) polymorphism on the susceptibility of depression and the efficacy of antidepressants. METHODS: A total of 275 patients with depression, who met the diagnostic criteria of both CCMD-3 and DSM-4, were randomly assigned into venlafaxine group (n=136)and paroxetine group(n=139). Another 202 healthy subjects were enrolled as the control group. Hamilton Rating...

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Identifiers

PMID: 23286405
DOI: 10.3881/j.issn.1000-503X.2012.06.011

Genes

APOE

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