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Article

Association between -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder.

Neuropsychobiology - 1 Jan 2002

Sato Kazuhiro, Yoshida Keizo, Takahashi Hitoshi, Ito Kenichi, Kamata Mitsuhiro, Higuchi Hisashi, Shimizu Tetsuo, Itoh Kunihiko, Inoue Kazuyuki, Tezuka Takehiko, Suzuki Toshio, Ohkubo Taashi, Sugawara Kazunobu, Otani Koichi

Abstract excerpt

Genetic polymorphism of the serotonin 5-HT(2A) receptor seems to be associated with therapeutic response to selective serotonin reuptake inhibitors (SSRIs). The present study investigated whether a novel -1438G/A polymorphism in the promoter region of the 5-HT(2A )receptor gene is associated with therapeutic response to fluvoxamine (an SSRI) in 66 Japanese patients with major depressive disorder. Fluvoxamine (50...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12422060
DOI: 10.1159/000066394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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