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Article

The haplotypes of the IRS-2 gene affect insulin sensitivity in Japanese patients with type 2 diabetes.

Diabetes research and clinical practice - 1 Apr 2005

Okazawa Kayoko, Yoshimasa Yasunao, Miyamoto Yoshihiro, Takahashi-Yasuno Akiko, Miyawaki Takashi, Masuzaki Hiroaki, Hayashi Tatsuya, Hosoda Kiminori, Inoue Gen, Nakao Kazuwa

Abstract excerpt

A commonly occurring nucleotide polymorphism of the insulin-receptor substrate 2 (IRS-2) gene at amino acid 1057 from Glycine to Asparaginic acid (G1057D) was recently shown to be a determinant of insulin sensitivity in both glucose-tolerant individuals and those with type 2 diabetes. With respec...

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Identifiers

PMID: 15811564
DOI: 10.1016/j.diabres.2004.08.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15811564-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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