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Article

Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.

The Journal of clinical endocrinology and metabolism - 1 Jan 2003

D'Alfonso Rossella, Marini Maria Adelaide, Frittitta Lucia, Sorge Roberto, Frontoni Simona, Porzio Ottavia, Mariani Luisa Marina, Lauro Davide, Gambardella Sergio, Trischitta Vincenzo, Federici Massimo, Lauro Renato, Sesti Giorgio

Abstract excerpt

We investigated the significance of Gly1057Asp and Leu647Val insulin receptor substrate (IRS)-2 polymorphisms in two Italian cohorts comprising 186 glucose-tolerant subjects and 240 subjects with type 2 diabetes from the Lazio region (i.e. representative of central Italy), and 123 glucose-tolerant subjects from the Sicily region (i.e. representative of south Italy). The allelic frequency of Gly1057Asp variant did...

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Identifiers

PMID: 12519871
DOI: 10.1210/jc.2002-020807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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