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Article

Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population.

International journal of andrology - 1 Apr 2005

Singh Kiran, Singh S K, Sah R, Singh Indu, Raman Rajiva

Abstract excerpt

A mutation (C677T) in the gene, MTHFR, is known to increase susceptibility to various multifactorial disorders. In order to assess this single nucleotide polymorphism (SNP) as risk factor for idiopathic male infertility, a case-control study was done on an Indian population. DNA from 151 cases of non-obstruction, idiopathic oligo-/azoospermia and 200 fertile males (controls) was polymerase chain reaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MTHFR gene

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 15811073
DOI: 10.1111/j.1365-2605.2004.00513.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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