Article
Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules.
The Journal of experimental medicine - 4 Apr 2005
Johansson Sofia, Johansson Maria, Rosmaraki Eleftheria, Vahlne Gustaf, Mehr Ramit, Salmon-Divon Mali, Lemonnier François, Kärre Klas, Höglund Petter
Abstract excerpt
The ability of murine NK cells to reject cells lacking self MHC class I expression results from an in vivo education process. To study the impact of individual MHC class I alleles on this process, we generated mice expressing single MHC class I alleles (K(b), D(b), D(d), or L(d)) or combinations...
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