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Article

APOA4 polymorphism as a risk factor for unfavorable lipid serum profile and depression: a cross-sectional study.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Aug 2011

Ota Vanessa Kiyomi, Chen Elizabeth Suchi, Ejchel Tatiana Flank, Furuya Tatiane Katsue, Mazzotti Diego Robles, Cendoroglo Maysa Seabra, Ramos Luiz Roberto, Araujo Lara Quirino, Burbano Rommel Rodriguez, Smith Marília de Arruda Cardoso

Abstract excerpt

INTRODUCTION: APOA1/C3/A4/A5 gene cluster is closely involved in lipid metabolism, and its polymorphisms have been associated with coronary heart disease and lipid plasma levels. Here, we aimed to investigate associations of APOC3 (3238C>G, -482C>T, 1100C>T) and APOA4 (Gln360His, Thr347Ser) polymorphisms in 382 individuals from a cohort of a Longitudinal Brazilian Elderly Study with major age-related morbidities...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21712729
DOI: 10.2310/JIM.0b013e31822467cd

Genes

APOA4
APOC3
APOA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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