Article
Sex-specific effects of the glutamine/histidine polymorphism in apo A-IV on HDL metabolism.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jul 1994
von Eckardstein A, Funke H, Chirazi A, Chen-Haudenschild C, Schulte H, Schönfeld R, Köhler E, Schwarz S, Steinmetz A, Assmann G
Abstract excerpt
In Caucasians, a histidine for glutamine substitution (Gln-->His) at residue 360 in apolipoprotein (apo) A-IV leads to an electrophoretically detectable polymorphism whose contribution to lipid metabolism regulation is controversial. In this study of 426 male and 188 female coronary heart disease...
Topics
- Aged
- Alleles
- Apolipoproteins A
- Carrier Proteins
- Cholesterol Ester Transfer Proteins
- Cholesterol, HDL
- Coronary Disease
- Female
- Gene Frequency
- Glutamine
- Glycoproteins
- Histidine
- Humans
- Male
- Middle Aged