Article
Polymorphisms in the promoter regions of FAS and FASL genes as candidate genetic factors conferring susceptibility to endometriosis.
International journal of molecular medicine - 1 May 2005
Fernández R M, Noval J A, García-Lozano J C, Borrego S, Moliní J L, Antiñolo G
Abstract excerpt
Although the pathophysiological mechanisms leading to endometriosis remain unknown, several hypothesis have been proposed, including a dysregulation of the normal apoptotic process which takes place in the endometrium. One of the apoptotic pathways playing a crucial role in the programmed cell death within the endometrium is the Fas-FasL system. In this study we have performed a case-control analysis in order to...
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