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Article

Relationship between Fas and Fas Ligand gene polymorphisms and pre-eclampsia.

The journal of obstetrics and gynaecology research - 1 Oct 2016

Masoumi Elham, Tavakkol-Afshari Jalil, Nikpoor Amin Reza, Ghaffari-Nazari Haniyeh, Tahaghoghi-Hajghorbani Sahar, Jalali Seyed Amir

Abstract excerpt

AIM: In normal pregnancy, the Th1 subtype, responsible for the production of inflammatory cytokines, is reduced, and the Th2 subtype is increased to prohibit inflammation. In pre-eclampsia, the Th1 cell population is increased; thus, subsequent inflammation and trophoblast destruction occur. Polymorphisms in the Fas and Fas Ligand (FasL) promoter regions can influence Fas and FasL expression and accused to...

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Identifiers

PMID: 27277758
DOI: 10.1111/jog.13062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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