Article
Variation in the hepatic gene expression in individual male Fischer rats.
Toxicologic pathology - 1 Jan 2005
Boorman Gary A, Irwin Richard D, Vallant Molly K, Gerken Diane K, Lobenhofer Edward K, Hejtmancik Milton R, Hurban Patrick, Brys April M, Travlos Greg S, Parker Joel S, Portier Christopher J
Abstract excerpt
A new tool beginning to have wider application in toxicology studies is transcript profiling using microarrays. Microarrays provide an opportunity to directly compare transcript populations in the tissues of chemical-exposed and unexposed animals. While several studies have addressed variation between microarray platforms and between different laboratories, much less effort has been directed toward individual...
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