Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis.

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Article

Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis.

The American journal of pathology - 1 May 1992

Young L H, Joag S V, Lin P Y, Luo S F, Zheng L M, Liu C C, Young J D

Abstract excerpt

To understand the role of cytolytic lymphocytes in the pathogenesis of rheumatoid arthritis, we investigated the expression of lymphocyte cytotoxicity mediators, perforin, and serine esterases, in lymphocytes derived from the synovial fluid of 15 patients with rheumatoid arthritis. Previous work...

Topics

Arthritis, Rheumatoid
Biopsy
Esterases
Female
Gene Expression
Humans
Interleukin-2
Leukocytes, Mononuclear
Lymphocytes
Male
Membrane Glycoproteins
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Perforin

Phenotype

Pore Forming Cytotoxic Proteins

Synovial Fluid

Synovial Membrane

Source

Open in PubMed Open full text

Identifiers

PMID: 1580335
PMCID: PMC1886510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1580335-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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