Article
High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane.
Arthritis and rheumatism - 1 Jul 1995
Cohen S B, Katsikis P D, Chu C Q, Thomssen H, Webb L M, Maini R N, Londei M, Feldmann M
Abstract excerpt
OBJECTIVE: To characterize the cytokine profile of the activated T cell population derived from the synovial membrane of rheumatoid arthritis (RA) patients. METHODS: Interleukin-2 (IL-2) was used to select for in vivo-activated T cells from the synovial membrane of 2 patients with RA, and the cells were cloned nonspecifically. The cytokine production profile of these clones was compared with that of clones...
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