High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane.

doi:10.1002/art.1780380710

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Article

High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane.

Arthritis and rheumatism - 1 Jul 1995

Cohen S B, Katsikis P D, Chu C Q, Thomssen H, Webb L M, Maini R N, Londei M, Feldmann M

Abstract excerpt

OBJECTIVE: To characterize the cytokine profile of the activated T cell population derived from the synovial membrane of rheumatoid arthritis (RA) patients. METHODS: Interleukin-2 (IL-2) was used to select for in vivo-activated T cells from the synovial membrane of 2 patients with RA, and the cells were cloned nonspecifically. The cytokine production profile of these clones was compared with that of clones...

Topics

Adult
Arthritis, Rheumatoid
Cells, Cultured
Female
Humans
Immunohistochemistry
Interferon-gamma
Interleukin-10
Interleukin-2
Interleukin-4
Lymphocyte Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Phenotype

Synovial Membrane

T-Lymphocytes

Tetradecanoylphorbol Acetate

Th1 Cells

Th2 Cells

Source

Open in PubMed

Identifiers

PMID: 7612044
DOI: 10.1002/art.1780380710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7612044-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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