Article
Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease.
Clinical and experimental immunology - 1 Dec 1994
Wu Z, Podack E R, McKenzie J M, Olsen K J, Zakarija M
Abstract excerpt
Infiltration of the thyroid gland by lymphocytes is a hall-mark of autoimmune thyroid disease; it is particularly evident in Hashimoto's thyroiditis but is also seen in most patients with Graves' disease. Infiltrating cells are comprised primarily of T lymphocytes, of which only a minority appear...
Topics
- Arthritis, Rheumatoid
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Graves Disease
- Humans
- Knee Joint
- Membrane Glycoproteins
- Perforin
- Phenotype
- Pore Forming Cytotoxic Proteins
- Receptors, Antigen, T-Cell, alpha-beta
- Reference Values
- Synovial Fluid
- T-Lymphocyte Subsets
- T-Lymphocytes
- Thyroid Gland
- Thyroiditis, Autoimmune