Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes.

The Journal of clinical endocrinology and metabolism - 1 Jun 2005

Hansen Sara K, Nielsen Eva-Maria D, Ek Jakob, Andersen Gitte, Glümer Charlotte, Carstensen Bendix, Mouritzen Peter, Drivsholm Thomas, Borch-Johnsen Knut, Jørgensen Torben, Hansen Torben, Pedersen Oluf

Abstract excerpt

The separate and combined effects of the PPARG Pro(12)Ala polymorphism and the KCNJ11 Glu(23)Lys polymorphisms on risk of type 2 diabetes were investigated in relatively large-scale, case-control studies. Separate effects of the variants were examined among 1187/1461 type 2 diabetic patients and 4791/4986 middle-aged, glucose-tolerant subjects. The combined analysis involved 1164 type 2 diabetic patients and 4733...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Glutamine

Share to Lysine

Share to Potassium Channels, Inwardly Rectifying

Share to PPAR gamma

Share to Proline

Source

Identifiers

PMID: 15797964
DOI: 10.1210/jc.2004-1942

Genes

KCNJ11
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes.PMID 15797964Read ↗

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.Semantic proximity Read ↗

Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the genes IRS1, KCNJ11, and PPARG2 in type 1 diabetes.Semantic proximity Read ↗

KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus.Semantic proximity Read ↗

Effect of genetic variants in KCNJ11, ABCC8, PPARG and HNF4A loci on the susceptibility of type 2 diabetes in Chinese Han population.Semantic proximity Read ↗

KCNJ11: Genetic Polymorphisms and Risk of Diabetes MellitusSemantic proximity Read ↗

The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis.Semantic proximity Read ↗

Combined effects of 17 common genetic variants on type 2 diabetes risk in a Han Chinese population.Semantic proximity Read ↗

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes.Semantic proximity Read ↗

Risk of type 2 diabetes and KCNJ11 gene polymorphisms: a nested case–control study and meta-analysisSemantic proximity Read ↗

Genetic polymorphisms in KCNJ11 (E23K, rs5219) and SDF-1β (G801A, rs1801157) genes are associated with the risk of type 2 diabetes mellitus.Semantic proximity Read ↗

The effect of KCNJ11 polymorphism on the risk of type 2 diabetes: a global meta-analysis based on 49 case-control studies.Semantic proximity Read ↗

Association between KCNJ11 E23K polymorphism and the risk of type 2 diabetes mellitus: A global meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.