Genetic polymorphisms in KCNJ11 (E23K, rs5219) and SDF-1β (G801A, rs1801157) genes are associated with the risk of type 2 diabetes mellitus.

doi:10.1080/09674845.2018.1473939

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Article

Genetic polymorphisms in KCNJ11 (E23K, rs5219) and SDF-1β (G801A, rs1801157) genes are associated with the risk of type 2 diabetes mellitus.

British journal of biomedical science - 1 Jul 2018

Rizvi S, Raza S T, Mahdi F, Singh S P, Rajput M, Rahman Q

Abstract excerpt

Background Type 2 diabetes mellitus (T2DM) is a global major health problem resulting from interaction of environmental and genetic factors, examples of the latter being KCNJ11 (coding for part of the ATP-sensitive potassium channel) and SDF-1β (coding for chemokine CXCL12). Our case-control study was conducted to assess whether recessive, dominant or additive genotype model associations of KCNJ11 (E23K, rs5219)...

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Source

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Identifiers

PMID: 29893194
DOI: 10.1080/09674845.2018.1473939

Genes

KCNJ11
CXCL12

Variants

rs5219
rs5219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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