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Article

Efficient mischarging of a viral tRNA-like structure and aminoacylation of a minihelix containing a pseudoknot: histidinylation of turnip yellow mosaic virus RNA.

Nucleic acids research - 25 Apr 1992

Rudinger J, Florentz C, Dreher T, Giegé R

Abstract excerpt

Mischarging of the valine specific tRNA-like structure of turnip yellow mosaic virus (TYMV) RNA has been tested in the presence of purified arginyl-, aspartyl-, histidinyl-, and phenylalanyl-tRNA synthetases from bakers' yeast. Important mischarging of a 264 nucleotide-long transcript was found with histidinyl-tRNA synthetase which can acylate this fragment up to a level of 25% with a loss of specificity...

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Identifiers

PMID: 1579487
DOI: 10.1093/nar/20.8.1865
PMCID: PMC312299

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