Article
The effect of RANTES chemokine genetic variants on early HIV-1 plasma RNA among African American injection drug users.
Journal of acquired immune deficiency syndromes (1999) - 15 Apr 2005
Duggal Priya, Winkler Cheryl A, An Ping, Yu Xiao-Fang, Farzadegan Homayoon, O'Brien Stephen J, Beaty Terri H, Vlahov David
Abstract excerpt
HIV-1 plasma RNA is a prognostic indicator of HIV-1, and increased levels of HIV-1 plasma RNA are associated with rapid progression to AIDS. Because chemokines and chemokine receptors are involved in the binding and entry of HIV-1, possible effects of host genetics on viral RNA levels should be visible in early infection. HIV-1 plasma RNA was measured within 2 years of seroconversion in 198 seroincident injection...
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