Article
RANTES Gene Polymorphisms Associated with HIV-1 Infections in Kenyan Population.
Disease markers - 1 Jan 2016
Mutuiri Shem P M, Kutima Helen L, Mwapagha Lamech M, Munyao James K, Nyamache Anthony Kebira, Wanjiru Irene, Khamadi Samoel A
Abstract excerpt
Previous studies have reported that two single nucleotide polymorphisms (SNPs) in the RANTES gene promoter region, -403G/A and -28C/G, are associated with a slower rate of decline in CD4+ T cell count. In addition, as a ligand of the major HIV coreceptor CCR5, it is known to block HIV-CCR5 interactions in the course of the HIV infection cycle. This study was carried out with the aim of determining the occurrence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.