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Is puberty an accelerator of type 1 diabetes in IL6-174CC females?

Diabetes - 1 Apr 2005

Gillespie Kathleen M, Nolsøe Runa, Betin Virginie M, Kristiansen Ole P, Bingley Polly J, Mandrup-Poulsen Thomas, Gale Edwin A M

Abstract excerpt

The pubertal peak in onset of type 1 diabetes occurs earlier in girls than boys. We postulated that this sex difference might be mediated in part by estrogen or by genes regulated by estrogen, such as the interleukin-6 (IL6) gene. Previous studies concerning the role of an estrogen-sensitive single nucleotide polymorphism (SNP) in the IL6 promoter in type 1 diabetes have proved contradictory. We therefore...

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Identifiers

PMID: 15793269
DOI: 10.2337/diabetes.54.4.1245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Is puberty an accelerator of type 1 diabetes in IL6-174CC females?PMID 15793269Read ↗

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