Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Compensatory Adaptation to the Loss of Biological Fitness Associated with Acquisition of Fusidic Acid Resistance in Staphylococcus aureus

25 Mar 2005

Abstract excerpt

Recent studies have shown that individual amino acid exchanges within elongation factor G (EF-G) cause fusidic acid resistance in Staphylococcus aureus. The data from the present study illustrate that the fusidic acid resistance-mediating amino acid substitutions P406L and H457Y are associated with a marked impairment of the biological fitness of S. aureus. In particular, strains producing EF-G derivatives with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial Genetics and Biotechnology
Share to Bacteriophages and microbial interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15793122
DOI: 10.1128/aac.49.4.1426-1431.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Compensatory Adaptation to the Loss of Biological Fitness Associated with Acquisition of Fusidic Acid Resistance in Staphylococcus aureusPMID 15793122Read ↗

Biological cost and compensatory evolution in fusidic acid-resistant Staphylococcus aureus.Semantic proximity Read ↗

Molecular analysis of fusidic acid resistance in Staphylococcus aureusSemantic proximity Read ↗

Mechanism of Elongation Factor-G-mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus aureusSemantic proximity Read ↗

Lysostaphin-resistant variants of Staphylococcus aureus demonstrate reduced fitness in vitro and in vivo.Semantic proximity Read ↗

The isoleucyl-tRNA synthetase mutation V588F conferring mupirocin resistance in glycopeptide-intermediate Staphylococcus aureus is not associated with a significant fitness burdenSemantic proximity Read ↗

Genetic Basis of Resistance to Fusidic Acid in StaphylococciSemantic proximity Read ↗

Increases in the mutation frequency at which fusidic acid-resistant Staphylococcus aureus arise with salicylate.Semantic proximity Read ↗

Increased overall antibiotic susceptibility in Staphylococcus aureus femAB null mutants.Semantic proximity Read ↗

Biological cost of rifampin resistance from the perspective of Staphylococcus aureus.Semantic proximity Read ↗

Cell wall monoglycine cross-bridges and methicillin hypersusceptibility in a femAB null mutant of methicillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.