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Genetic Basis of Resistance to Fusidic Acid in Staphylococci

27 Feb 2007

Abstract excerpt

Resistance to fusidic acid in Staphylococcus aureus often results from acquisition of the fusB determinant or from mutations in the gene (fusA) that encodes the drug target (elongation factor G). We now report further studies on the genetic basis of resistance to this antibiotic in the staphylococci. Two staphylococcal genes that encode proteins exhibiting ca. 45% identity with FusB conferred resistance to...

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PMID: 17325218
DOI: 10.1128/aac.01542-06

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