Increases in the mutation frequency at which fusidic acid-resistant Staphylococcus aureus arise with salicylate.

Abstract excerpt

Salicylate was shown to increase the frequency at which a fusidic acid-susceptible strain of Staphylococcus aureus underwent mutation to become fusidic acid-resistant. These fusidic acid-resistant mutants had alterations in spectinomycin and kanamycin resistance levels indicative of mutations in fusA, the gene that encodes elongation factor-G, the target of fusidic acid.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anti-Bacterial Agents
• Share to Drug Resistance, Microbial
• Share to Microbial Sensitivity Tests