Article
Regulation of the human atrial myosin light chain 1 promoter by Ca2+-calmodulin-dependent signaling pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Apr 2005
Woischwill Christiane, Karczewski Peter, Bartsch Holger, Luther Hans-Peter, Kott Monika, Haase Hannelore, Morano Ingo
Abstract excerpt
We investigated expression regulation of the human atrial myosin light chain 1 (hALC-1) gene using a cardiomyocyte H9c2 cell line stably transfected with a construct consisting of the human ALC-1 promoter cloned in front of the luciferase gene (H9c2T1). H9c2T1 cells were stimulated with vasopressin, which is known to induce cardiomyocyte hypertrophy and to activate a panel of signaling pathways. Those pathways...
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