Article
Tumour necrosis factor receptors (TNFRs) in Type 2 diabetes. Analysis of soluble plasma fractions and genetic variations of TNFR2 gene in a case-control study.
Diabetic medicine : a journal of the British Diabetic Association - 1 Apr 2005
Vendrell J, Broch M, Fernandez-Real J M, Gutiérrez C, Simón I, Megia A, Gallart L, Ricart W, Richart C
Abstract excerpt
AIMS: We have studied the relationships between soluble fractions of tumour necrosis factor receptors (sTNFR1 and sTNFR2) in Type 2 diabetes (DM2) and its chronic microvascular complications. Likewise, we have analysed the genetic susceptibility of 196T > G exon6/CA-repeat intron 4 mutations in the TNFR2 gene in this population. METHODS: A case-control study was conducted to examine the role of sTNFRs in 345 DM2...
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