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Article

Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction.

Circulation - 29 Mar 2005

Pelzer Theo, Loza Paula-Anahi Arias, Hu Kai, Bayer Barbara, Dienesch Charlotte, Calvillo Laura, Couse John F, Korach Kenneth S, Neyses Ludwig, Ertl Georg

Abstract excerpt

BACKGROUND: Lower mortality rates among women with chronic heart failure than among men may depend in part on the action of female sex hormones, especially estrogens. The biological effects of estrogens are mediated by 2 distinct estrogen receptor (ER) subtypes (ERalpha and ERbeta). The present study was undertaken to determine the role of ERbeta in the development of chronic heart failure after experimental...

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Identifiers

PMID: 15781739
DOI: 10.1161/01.CIR.0000159262.18512.46

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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