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Article

Estrogen receptor-alpha mediates acute myocardial protection in females.

American journal of physiology. Heart and circulatory physiology - 1 Jun 2006

Wang Meijing, Crisostomo Paul, Wairiuko George M, Meldrum Daniel R

Abstract excerpt

Sex differences in myocardial recovery have been reported after acute ischemia and reperfusion injury. Estrogen and the estrogen receptor are critical determinants of cardiovascular sex differences. However, the mechanistic pathways responsible for these differences remain unknown. We hypothesized that estrogen receptor-alpha is an important modulator of 1) myocardial functional recovery after ischemia and 2)...

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Identifiers

PMID: 16415070
DOI: 10.1152/ajpheart.01219.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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