Article
Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.
The Journal of biological chemistry - 10 Jun 2005
Galibert Laurent, Diemer Geoffrey S, Liu Zhi, Johnson Richard S, Smith Jeffrey L, Walzer Thierry, Comeau Michael R, Rauch Charles T, Wolfson Martin F, Sorensen Rick A, Van der Vuurst de Vries Anne-Renée, Branstetter Daniel G, Koelling Raymond M, Scholler John, Fanslow William C, Baum Peter R, Derry Jonathan M, Yan Wei
Abstract excerpt
Dendritic cells (DCs) are a phenotypically and functionally heterogenous population of leukocytes with distinct subsets serving a different set of specialized immune functions. Here we applied an in vitro whole cell panning approach using antibody phage display technology to identify cell-surface epitopes specifically expressed on human blood BDCA3(+) DCs. A single-chain antibody fragment (anti-1F12 scFv) was...
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