Influence of viral load and genotype in the progression of Hepatitis B-associated liver cirrhosis to hepatocellular carcinoma.

doi:10.1111/j.1478-3231.2005.01077.x

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Article

Influence of viral load and genotype in the progression of Hepatitis B-associated liver cirrhosis to hepatocellular carcinoma.

Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2005

Mahmood Sabina, Niiyama Gouichi, Kamei Ayumi, Izumi Akiyoshi, Nakata Keiichi, Ikeda Hideji, Suehiro Mitsuhiko, Kawanaka Miwa, Togawa Kazumi, Yamada Gotaro

Abstract excerpt

AIM/BACKGROUND: Hepatitis B virus (HBV) is an important factor in the development of hepatocellular carcinoma (HCC). We studied the influence of HBV viral load on HCC occurrence in HBV related liver cirrhosis (LC). PATIENTS AND METHODS: Ninety-one LC patients were followed up over a period of 7 years. Twenty three patients received Interferon (IFN) therapy. RESULTS: In 7 years, 23 patients developed HCC. Of them...

Topics

Adult
Age Distribution
Aged
Aged, 80 and over
Analysis of Variance
Biopsy, Needle
Carcinoma, Hepatocellular
Case-Control Studies
Cohort Studies
DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Disease Progression

Female

Genotype

Hepatitis B, Chronic

Hepatitis C, Chronic

Humans

Liver Cirrhosis

Liver Neoplasms

Source

Open in PubMed

Identifiers

PMID: 15780042
DOI: 10.1111/j.1478-3231.2005.01077.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15780042-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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