Article
Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease.
Hepatology (Baltimore, Md.) - 1 Jan 2003
Sumi Hajime, Yokosuka Osamu, Seki Naohiko, Arai Makoto, Imazeki Fumio, Kurihara Tomoko, Kanda Tatsuo, Fukai Kenichi, Kato Masaki, Saisho Hiromitsu
Abstract excerpt
To investigate the hepatitis B virus (HBV) genotype-related differences in the progression of liver disease, 585 patients with chronic HBV infection including 258 with histologically verified chronic liver disease (CLD) and 74 with hepatocellular carcinoma (HCC) were examined. The mean ages of both patients with advanced fibrosis (F3 or F4) and with HCC were significantly older in genotype B than in genotype C...
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