Article
Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma.
Journal of hepatology - 1 Jan 2007
Lin Shi-Ming, Yu Ming-Lung, Lee Chuan-Mo, Chien Rong-Nan, Sheen I-Shyan, Chu Chia-Ming, Liaw Yun-Fan
Abstract excerpt
BACKGROUND/AIMS: The long-term outcomes of interferon-alpha (IFN-alpha) therapy in hepatitis B e antigen (HBeAg) seropositive patients remain controversial. This study was conducted to address this issue. METHODS: The long-term outcomes were compared in 233 IFN-treated patients and 233 well-matched untreated controls. RESULTS: The cumulative incidence at the end of 15 years of follow-up (median 6.8 years, range...
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