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Article

Characterization of Mammalian Selenoproteomes

29 May 2003

Abstract excerpt

In the genetic code, UGA serves as a stop signal and a selenocysteine codon, but no computational methods for identifying its coding function are available. Consequently, most selenoprotein genes are misannotated. We identified selenoprotein genes in sequenced mammalian genomes by methods that rely on identification of selenocysteine insertion RNA structures, the coding potential of UGA codons, and the presence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12775843
DOI: 10.1126/science.1083516

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