Article
SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development.
Journal of bacteriology - 1 Apr 2005
Tormo María Angeles, Martí Miguel, Valle Jaione, Manna Adhar C, Cheung Ambrose L, Lasa Iñigo, Penadés José R
Abstract excerpt
Staphylococcus epidermidis biofilm formation is associated with the production of the polysaccharide intercellular adhesin (PIA)--poly-N-acetylglucosamine polysaccharide (PNAG) by the products of the icaADBC operon. Recent evidence indicates that SarA, a central regulatory element that controls the production of Staphylococcus aureus virulence factors, is essential for the synthesis of PIA/PNAG and the ensuing...
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