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Article

The Functional Study of Response Regulator ArlR Mutants in Staphylococcus Aureus.

Applied biochemistry and biotechnology - 1 Nov 2024

Zhou Jinhong, Refat Moath, Guo Yucheng, Zhang Jiaxin, Jiao Min, He Wenbo, He Xiaoyu, Rabie Mai A, Ouyang Zhenlin, Zheng Fang

Abstract excerpt

Staphylococcus aureus is a major cause of hospital-associated infections worldwide. The organism's ability to form biofilms has led to resistance against current treatment options such as beta-lactams, glycopeptides, and daptomycin. The ArlRS two-component system is a crucial regulatory system necessary for S. aureus autolysis, biofilm formation, capsule synthesis, and virulence. This study aims to investigate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38530540
DOI: 10.1007/s12010-024-04919-1
PMCID: PMC11645427

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