Article
[p53 gene codon 72 polymorphism and genetic susceptibility to hepatocellular carcinoma in Chinese population].
Zhonghua yi xue za zhi - 12 Jan 2005
Zhu Zhong-Zheng, Cong Wen-Ming, Liu Shu-Fang, Dong Hui, Zhu Guan-Shan, Wu Meng-Chao
Abstract excerpt
OBJECTIVE: To investigate the possible association between the p53 Arg72Pro polymorphism and susceptibility to hepatocellular carcinoma (HCC) in Chinese population. METHODS: Genomic DNA of the normal liver tissues was extracted from 507 patients with HCC confirmed by histopathological examination and 541 patients with benign liver diseases. PCR-based restriction fragment length polymorphism (RFLP) method was used...
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