Article
[p53 gene codon 72 polymorphism and susceptibility to keloid in Chinese population].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery - 1 Jan 2005
Zhuo Yang, Gao Jianhua, Luo Shenqiu, Zeng Weisen, Hu Zhiqi, Lu Feng, Zhao Yongzhong
Abstract excerpt
OBJECTIVE: To investigate the relationship between p53 codon 72 polymorphism and susceptibility to keloid. METHODS: The p53 genotypes were detected by polymerase chain reaction-reverse dot blot (PCR-RDB) and DNA direct sequencing among 15 healthy controls and 15 patients with keloid. RESULTS: The frequency of the Pro allele (P = 0.035) and Pro/Pro genotype (P = 0.030) in patients was significantly higher than...
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