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Article

Skeletal and cardiac muscle defects in a murine model of Emery-Dreifuss muscular dystrophy.

Novartis Foundation symposium - 1 Jan 2005

Grattan M J, Kondo C, Thurston J, Alakija P, Burke B J, Stewart C, Syme D, Giles W R

Abstract excerpt

Previous histological findings, physiological data, and behavioral observations on the A-type lamin knockout mouse (Lmna(-/-)) suggest that important aspects of this model resemble the human Emery-Dreifuss muscular dystrophy (EDMD) phenotype. The main goal of our experiments was to study skeletal and cardiac muscle function in this murine model to obtain the semiquantitative data needed for more detailed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15773751
DOI: 10.1002/0470093765.ch9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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