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Associations of Baseline Blood Pressure Levels and Efficacy of Benazepril Treatment with Interaction of α-Adducin and ACE Gene Polymorphisms in Hypertensives

1 Jan 2005

Abstract excerpt

The molecular mechanisms underlying essential hypertension are not fully elucidated. Although Benazepril is being widely used in antihypertensive medication, the agent is efficacious in only a portion of hypertensive patients. To evaluate the interaction of alpha-adducin gene Gly460Trp and angiotensin I-converting enzyme (ACE) gene I/D polymorphisms in regard to baseline blood pressure (BP) levels and the...

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PMID: 15773232
DOI: 10.1081/ceh-200044273

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