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DNA DEGRADATION IN DEVELOPMENT AND PROGRAMMED CELL DEATH

17 Dec 2004

Abstract excerpt

Most mammalian cells have nuclei that contain DNA, which replicates during cell proliferation. DNA is destroyed by various developmental processes in mammals. It is degraded during programmed cell death that accompanies mammalian development. The nuclei of erythrocytes and eye lens fiber cells are also removed during their differentiation into mature cells. If DNA is not properly degraded in these processes, it...

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Identifiers

PMID: 15771588
DOI: 10.1146/annurev.immunol.23.021704.115811

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