Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intracellular drug sequestration events associated with the emergence of multidrug resistance: a mechanistic review

1 Jan 2005

Abstract excerpt

The acquisition of multi-drug resistance (MDR) in cancer cells subjected to anticancer agents remains a formidable obstacle to successful therapeutic outcomes in cancer patients. As the name implies, the resistance phenotype (MDR) is not typically limited to the drug initially used to eradicate cancer but is often transferred to structurally unrelated chemotherapeutic agents. The mechanisms underlying the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to Drug Transport and Resistance Mechanisms
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15769640
DOI: 10.2741/1634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intracellular drug sequestration events associated with the emergence of multidrug resistance: a mechanistic reviewPMID 15769640Read ↗

Multidrug Resistance: Are We Still Afraid of the Big Bad WolfSemantic proximity Read ↗

The Emergence of Drug Transporter-Mediated Multidrug Resistance to Cancer ChemotherapySemantic proximity Read ↗

Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolismSemantic proximity Read ↗

Mechanisms and insights into drug resistance in cancerSemantic proximity Read ↗

Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance.Semantic proximity Read ↗

Drug resistance in human cancers - Mechanisms and implications.Semantic proximity Read ↗

Mechanisms of Multidrug Resistance in Cancer ChemotherapySemantic proximity Read ↗

Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancersSemantic proximity Read ↗

Intracellular trafficking of MDR transporters and relevance of SNPs.Semantic proximity Read ↗

ATP‐binding cassette (ABC) transporters in cancer: A review of recent updatesSemantic proximity Read ↗

Multidrug Resistance in Cancer: Its Mechanism and its ModulationSemantic proximity Read ↗

Drug resistance: from bacteria to cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.