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Article

Variation in genomic Alu repeat density as a basis for rapid construction of low resolution physical maps of human chromosomes.

Chromosoma - 1 Mar 1992

Lane M J, Waterbury P G, Carroll W T, Smardon A M, Faldasz B D, Peshick S M, Mante S, Huckaby C S, Kouri R E, Hanlon D J

Abstract excerpt

Human DNA restriction fragments containing high numbers of Alu repeat sequences can be preferentially detected in the presence of other human DNA restriction fragments in DNA from human: rodent somatic cell hybrids when the DNA is fragmented with enzymes that cleave mammalian DNA infrequently. This ability to lower the observed human DNA complexity allowed us to develop an approach to order rapidly somatic hybrid...

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PMID: 1576885
DOI: 10.1007/BF00346014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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