Article
Silhouette scores for assessment of SNP genotype clusters.
BMC genomics - 10 Mar 2005
Lovmar Lovisa, Ahlford Annika, Jonsson Mats, Syvänen Ann-Christine
Abstract excerpt
BACKGROUND: High-throughput genotyping of single nucleotide polymorphisms (SNPs) generates large amounts of data. In many SNP genotyping assays, the genotype assignment is based on scatter plots of signals corresponding to the two SNP alleles. In a robust assay the three clusters that define the genotypes are well separated and the distances between the data points within a cluster are short. "Silhouettes" is a...
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