Article
Association of micropenis with Pro185Ala polymorphism of the gene for aryl hydrocarbon receptor repressor involved in dioxin signaling.
Endocrine journal - 1 Feb 2005
Soneda Shun, Fukami Maki, Fujimoto Masatoshi, Hasegawa Tomonobu, Koitabashi Yasushi, Ogata Tsutomu
Abstract excerpt
The prevalence of undermasculinized external genitalia has increased in several countries including Japan, and this phenomenon has primarily been ascribed to the deleterious effects of environmental endocrine disruptors such as dioxins. To examine a possible role of the genetic susceptibility to dioxins in the development of micropenis (MP), we studied the Arg554Lys polymorphism of the gene for aryl hydrocarbon...
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