Article
Genetic modification of the association between peripubertal dioxin exposure and pubertal onset in a cohort of Russian boys.
Environmental health perspectives - 1 Jan 2013
Humblet Olivier, Korrick Susan A, Williams Paige L, Sergeyev Oleg, Emond Claude, Birnbaum Linda S, Burns Jane S, Altshul Larisa M, Patterson Donald G, Turner Wayman E, Lee Mary M, Revich Boris, Hauser Russ
Abstract excerpt
BACKGROUND: Exposure to dioxins has been associated with delayed pubertal onset in both epidemiologic and animal studies. Whether genetic polymorphisms may modify this association is currently unknown. Identifying such genes could provide insight into mechanistic pathways. This is one of the first studies to assess genetic susceptibility to dioxins. OBJECTIVES: We evaluated whether common polymorphisms in genes...
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