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Article

Na,K-ATPase from mice lacking the gamma subunit (FXYD2) exhibits altered Na+ affinity and decreased thermal stability.

The Journal of biological chemistry - 13 May 2005

Jones D Holstead, Li Tony Y, Arystarkhova Elena, Barr Kevin J, Wetzel Randall K, Peng Jun, Markham Kathryn, Sweadner Kathleen J, Fong Guo-Hua, Kidder Gerald M

Abstract excerpt

The gamma subunit of the Na,K-ATPase, a 7-kDa single-span membrane protein, is a member of the FXYD gene family. Several FXYD proteins have been shown to bind to Na,K-ATPase and modulate its properties, and each FXYD protein appears to alter enzyme kinetics differently. Different results have sometimes been obtained with different experimental systems, however. To test for effects of gamma in a native tissue...

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Source

Identifiers

PMID: 15755730
DOI: 10.1074/jbc.M500697200

Genes

FXYD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Na,K-ATPase from mice lacking the gamma subunit (FXYD2) exhibits altered Na+ affinity and decreased thermal stability.PMID 15755730Read ↗

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