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Article

Differential regulation of renal Na,K-ATPase by splice variants of the gamma subunit.

The Journal of biological chemistry - 22 Mar 2002

Arystarkhova Elena, Donnet Claudia, Asinovski Natalya K, Sweadner Kathleen J

Abstract excerpt

Sodium and potassium-exchanging adenosine triphosphatase (Na,K-ATPase) in the kidney is associated with the gamma subunit (gamma, FXYD2), a single-span membrane protein that modulates ATPase properties. Rat and human gamma occur in two splice variants, gamma(a) and gamma(b), with different N termini. Here we investigated their structural heterogeneity and functional effects on Na,K-ATPase properties. Both forms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11756431
DOI: 10.1074/jbc.M111552200

Genes

FXYD2
NRK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential regulation of renal Na,K-ATPase by splice variants of the gamma subunit.PMID 11756431Read ↗

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