Article
H+,K+-ATPase.
Current opinion in nephrology and hypertension - 1 Sept 1999
DuBose T D, Gitomer J, Codina J
Abstract excerpt
The H+,K+-ATPases comprise a group of integral membrane proteins that belong to the X+,K+-ATPase subfamily of P-type cation-transporting ATPases. Although these H+,K+-ATPase isoforms share approximately 60-70% amino acid identity, they exhibit discrete kinetic and pharmacological properties when expressed in heterologous systems. HK alpha2 has been categorized by its insensitivity to Sch-28080, an inhibitor of...
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